A universal compressor for genomic files
- Use cases
- Using genozip
- Using genounzip
- Using genocat
- Using genols
- Publications & Citing
- Source code
- Developer options
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Genozip is a universal compressor for genomic files - it is optimized to compress FASTQ, SAM/BAM/CRAM, VCF/BCF, FASTA, GVF, PHYLIP, Chain and 23andMe files, but it can also compress any other file (including non-genomic files).
Typically, a 2X-5X improvement over the existing compression is achieved when compressing already-compressed files like .fastq.gz .bam vcf.gz, and much higher ratios in some other cases.
Yes, Genozip can compress already-compressed files (.gz .bz2 .xz .bam .cram).
The compression is lossless - the decompressed file is 100% identical to the original file (some exceptions apply).
Genozip consists of four command line tools:
genozip compresses files
genounzip decompresses files
genols shows metadata of compressed files and directories
- genocat is the workhorse for using genozip in analytical pipelines:
Display the contents of a compressed file - possibly piping it into a downstream tool
Subset a compressed file - show a specific part of its contents
Translate a compressed file to another format (eg BAM to FASTQ or Multi-FASTA to Phylip)
- From Conda (Linux & Mac):
conda config --add channels conda-forge
conda install genozip
Using a Windows installer:
- From Github (tested on Linux, Mac and Windows):
git clone https://github.com/divonlan/genozip
makerequires: gcc or clang, make
- From Docker Hub here
Publications & Citing¶
Lan, D., et al. (2021) Genozip: a universal extensible genomic data compressor Bioinformatics, btab102, https://doi.org/10.1093/bioinformatics/btab102
Lan, D., et al. (2020) genozip: a fast and efficient compression tool for VCF files Bioinformatics, 36, 4091–4092
Bug reports and feature requests: firstname.lastname@example.org
Commercial license inquiries: email@example.com
Requests for support for compression of additional public or proprietary file formats: firstname.lastname@example.org
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